BME 408 | Course Introduction and Application Information - Department of Genetics and Bioengineering

Course Name

Biomedical Polymer Technologies

Code	Semester	Theory (hour/week)	Application/Lab (hour/week)	Local Credits	ECTS
BME 408	Fall/Spring	3	0	3	5

Prerequisites	None
Course Language	English
Course Type	Elective
Course Level	First Cycle
Mode of Delivery	-
Teaching Methods and Techniques of the Course	-
National Occupation Classification	-
Course Coordinator	Dr. Öğr. Üyesi Burçak Alp
Course Lecturer(s)	Dr. Öğr. Üyesi Burçak Alp
Assistant(s)	-

Course Objectives

The aim of this course is to introduce the students with the polymers used in biomedical field. The course covers the synthesis and characterization of polymers, properties of polymers and the choice of polymers depending on particular biomedical problems. The course will also cover the types of polymers used in medical and drug delivery applications before discussing the future of biomedical polymers.

Learning Outcomes

#	Content	PC Sub	* Contribution Level
#	Content	PC Sub	1	2	3	4	5
1	list natural and synthetic polymers used in biomedical science
2	define explain types and properties of biopolymers
3	explain the methods used in characterization of polymers
4	explain the methods used in synthesis and modification of polymers
5	discuss about the choice of polymers used in drug delivery
6	define degeneration of polymers within the human body
7	solve problems related to development of polymers for various biomedical applications
8	discuss the innovations and trending technologies in the field of biopolymers.

Course Description

Introduction to polymer science, properties of polymers, polymerisation techniques, characterisation of polymers, biomedical applications of polymers, Biopolymer processing, drug delivery systems, biodegredation and biodeterioration, chemical synthesis of biopolymers, synthesis of natural biopolymers, and future of biomedical applications of polymers.

Course Category	Core Courses
	Major Area Courses
	Supportive Courses
	Media and Management Skills Courses
	Transferable Skill Courses

Week	Subjects	Related Preparation	Learning Outcome
1	Introduction to Polymer Science	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 1
2	The Use of Polymers in Health Science	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 1
3	Characterization of Polymers	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 2.1,2
4	Characterization of Polymers	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 2.1,2
5	Structures and Features of Polymers	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 2.3,4
6	Synthesis of Polymers	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 3.1-2
7	Polymerization	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 3.2-6
8	Midterm
9	Polymer Modifications	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 3.9
10	Biodegradable and Bioerodible Polymers	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 4.3
11	Biomedical Use of Polymers	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 4.3
12	Pharmaceutical Use of Polymers	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5, Chapter 4.4
13	DNA Matrixes	Dan Luo, W. Mark Saltzman, Synthetic DNA delivery systems, Nature Biotechnology 18, 33 - 37 (2000) doi:10.1038/71889
14	Future directions	Dan Luo, W. Mark Saltzman, Synthetic DNA delivery systems, Nature Biotechnology 18, 33 - 37 (2000) doi:10.1038/71889
15	Review
16	Review of the Semester

Course Notes/Textbooks	Denis J-P Labarre, Gilles Ponchel, Christine Vauthier, Biomedical and Pharmaceutical Polymers, Pharmaceutical Press, 2011, ISBN 978 0 85369 730 5 Course slides
Suggested Readings/Materials	Johnson, R.M., Mwaikambo, L.Y., and Tucker, N. “Biopolymers”, Vol.14, No.3, Rapra Review Reports, (2003).

Semester Activities	Number	Weighting	LO 1	LO 2	LO 3	LO 4	LO 5	LO 6	LO 7	LO 8
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques	1	15
Portfolio
Homework / Assignments	1	15
Presentation / Jury	1	10
Project
Seminar / Workshop
Oral Exams
Midterm	1	20
Final Exam	1	40
Total

Weighting of Semester Activities on the Final Grade	4	60
Weighting of End-of-Semester Activities on the Final Grade	1	40
Total

Semester Activities	Number	Duration (Hours)	Workload
Theoretical Course Hours (Including exam week: 16 x total hours)	16	3	48
Laboratory / Application Hours (Including exam week: '.16.' x total hours)	16	2	32
Study Hours Out of Class			0
Field Work			0
Quizzes / Studio Critiques	1	15	15
Portfolio			0
Homework / Assignments	1	10	10
Presentation / Jury	1	10	10
Project			0
Seminar / Workshop			0
Oral Exam			0
Midterms	1	15	15
Final Exam	1	20	20
		Total	150

#	PC Sub	Program Competencies/Outcomes	* Contribution Level
#	PC Sub	Program Competencies/Outcomes	1	2	3	4	5
1	To have adequate knowledge in Mathematics, Science and Genetics and Bioengineering; to be able to use theoretical and applied information in these areas on complex engineering problems.		-	-	-	-	-
2	To be able to identify, define, formulate, and solve complex Genetics and Bioengineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.		-	-	-	-	-
3	To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.		-	-	-	-	-
4	To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Genetics and Bioengineering applications; to be able to use information technologies effectively.		-	-	-	-	-
5	To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Genetics and Bioengineering research topics.		-	-	-	-	-
6	To be able to work efficiently in Genetics and Bioengineering disciplinary and multi-disciplinary teams; to be able to work individually.		-	-	-	-	-
7	To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.		-	-	-	-	-
8	To have knowledge about global and social impact of Genetics and Bioengineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of Genetics and Bioengineering solutions.		-	-	-	-	-
9	To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in Genetics and Bioengineering applications.		-	-	-	-	-
10	To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.		-	-	-	-	-
11	To be able to collect data in the area of Genetics and Bioengineering, and to be able to communicate with colleagues in a foreign language.		-	-	-	-	-
12	To be able to speak a second foreign language at a medium level of fluency efficiently.		-	-	-	-	-
13	To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Genetics and Bioengineering.		-	-	-	-	-