FACULTY OF ENGINEERING

Department of Genetics and Bioengineering

GBE 208 | Course Introduction and Application Information

Course Name
General and Molecular Biology 2
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
GBE 208
Spring
2
2
3
5

Prerequisites
  GBE 100 To attend the classes (To enrol for the course and get a grade other than NA or W)
Course Language
English
Course Type
Required
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course Discussion
Group Work
Q&A
Lecture / Presentation
Course Coordinator
Course Lecturer(s)
Assistant(s)
Course Objectives This course will examine the internal organization of the eukaryotic cell, organelle and membrane function, cell-cell adhesion, the structure and function of cytoskeleton and the extracellular matrix. In this course we will cover topics such as membrane structure and composition, transport, and trafficking; the cytoskeleton and cell movement; the integration of cells into tissues and important cellular processes such as cell cycle regulation, apoptosis, regeneration and repair and cancer cell biology.
Learning Outcomes The students who succeeded in this course;
  • Define cell structure and cytoskeleton, cell-cell and cell-ECM adhesion and how it relates to cell functions.
  • Explain how cellular transport and secretion are achieved.
  • Explain how cells grow, divide, and die and how these important processes are regulated.
  • Discuss how dysregulation of cellular processes leads to cancer and other diseases.
  • Define different types of stem cells and their role in tissue regeneration and repair processes.
  • Apply the iPSCs technology to establish new disease models
Course Description The internal organization of the eukaryotic cell, organelle and membrane function, cell-cell signaling, cell transport and secretion, the extracellular matrix, cell division and apoptosis will be introduced. Also, stem cells, tissue regeneration and repair and iPSCs technology will also be explained.

 



Course Category

Core Courses
X
Major Area Courses
Supportive Courses
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Cell structure and organelles Molecular Biology of the Cell, 6th edition, Garland Science. ISBN 9780815344643 Chapters 1 & 2
2 Cell membrane and transport Molecular Biology of the Cell, Chapters 10 & 11
3 Cellular secretion and Vesicular Transport Molecular Biology of the Cell, Chapters 12 & 13
4 Protein Secretory Pathways Molecular Biology of the Cell, Chapter 13
5 Extracellular Matrix Molecular Biology of the Cell, Chapter 19
6 Midterm I
7 Cell-cell and Cell-ECM Adhesion Molecular Biology of the Cell, Chapter 19
8 Cell-cell Interaction Molecular Biology of the Cell, Chapter 15
9 Cell growth and division Molecular Biology of the Cell, Chapter 17
10 Cell death Molecular Biology of the Cell, Chapter 18
11 Tissue repair and regeneration Molecular Biology of the Cell, Chapter 22
12 Midterm II
13 Stem Cells Molecular Biology of the Cell, Chapter 22
14 Cancer Molecular Biology of the Cell, Chapter 22
15 Presentations
16 Final Exam

 

Course Notes/Textbooks

Alberts et.al, Molecular Biology of the Cell, 6th edition, Garland Science. 

ISBN 9780815344643
Suggested Readings/Materials

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
1
10
Portfolio
Homework / Assignments
Presentation / Jury
1
10
Project
1
10
Seminar / Workshop
Oral Exams
Midterm
1
30
Final Exam
1
40
Total

Weighting of Semester Activities on the Final Grade
4
60
Weighting of End-of-Semester Activities on the Final Grade
1
40
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 16 x total hours)
16
2
32
Laboratory / Application Hours
(Including exam week: '.16.' x total hours)
16
2
32
Study Hours Out of Class
0
Field Work
0
Quizzes / Studio Critiques
1
15
15
Portfolio
0
Homework / Assignments
0
Presentation / Jury
1
14
14
Project
1
14
14
Seminar / Workshop
0
Oral Exam
0
Midterms
1
20
20
Final Exam
1
23
23
    Total
150

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

To have adequate knowledge in Mathematics, Science and Genetics and Bioengineering; to be able to use theoretical and applied information in these areas on complex engineering problems.

X
2

To be able to identify, define, formulate, and solve complex Genetics and Bioengineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.

3

To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.

X
4

To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Genetics and Bioengineering applications; to be able to use information technologies effectively.

X
5

To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Genetics and Bioengineering research topics.

6

To be able to work efficiently in Genetics and Bioengineering disciplinary and multi-disciplinary teams; to be able to work individually.

X
7

To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.

8

To have knowledge about global and social impact of Genetics and Bioengineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of Genetics and Bioengineering solutions.

9

To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in Genetics and Bioengineering applications.

10

To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.

11

To be able to collect data in the area of Genetics and Bioengineering, and to be able to communicate with colleagues in a foreign language.

12

To be able to speak a second foreign language at a medium level of fluency efficiently.

13

To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Genetics and Bioengineering.

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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