GBE 210 | Course Introduction and Application Information - Department of Genetics and Bioengineering

Course Name

Bioengineering Thermodynamics and Kinetics

Code	Semester	Theory (hour/week)	Application/Lab (hour/week)	Local Credits	ECTS
GBE 210	Spring	2	2	3	5

Prerequisites	None
Course Language	English
Course Type	Required
Course Level	First Cycle
Mode of Delivery	-
Teaching Methods and Techniques of the Course	Problem Solving Q&A Lecture / Presentation
National Occupation Classification	-
Course Coordinator	-
Course Lecturer(s)	Öğr. Gör. Dr. Gülizar ÇALIŞKAN BİLGİN
Assistant(s)	Araş. Gör. Mehmet Serdar Çakan

Course Objectives

The objective of this course is to teach the basic concepts and laws of thermodynamics and the basic principles of reaction kinetics and to explain their applications in bioengineering.

Learning Outcomes

#	Content	PC Sub	* Contribution Level
#	Content	PC Sub	1	2	3	4	5
1	Define the basic concepts and laws of thermodynamics.
2	Use property tables and equations of state in the evaluation of thermodynamic properties.
3	Apply mass and energy balances, and the first law of thermodynamics in the solution of engineering problems.
4	Determine the rate and order of a reaction.
5	Explain the applications of thermodynamic laws and reaction kinetics in bioengineering.

Course Description

This course covers energy forms, thermodynamic laws, property tables, equations of state, internal energy, specific heat, enthalpy, conservation of mass and energy, reaction kinetics and mechanisms, entropy and free energy concepts, and applications of thermodynamic laws and reaction kinetics in bioengineering.

Course Category	Core Courses	X
	Major Area Courses
	Supportive Courses
	Media and Management Skills Courses
	Transferable Skill Courses

Week	Subjects	Related Preparation	Learning Outcome
1	Introduction to thermodynamics and basic concepts	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 1
2	Forms of energy and energy transfer by heat and work, general concepts of bio-heat transfer	• Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 2 • Truskey, GA; Yuan, F; Katz, DF, ‘‘Transport Phenomena in Biological Systems (2nd Edition)’’, Pearson Prentice Hall Bioengineering, New Jersey, USA, 2010. Chapter 17
3	The first law of thermodynamics, conservation and conversion of energy	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 2
4	Properties of pure substances, phase-change processes	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 3
5	Property tables and equations of state	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 3
6	Energy analysis of closed systems, internal energy, enthalpy and specific heat	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 4
7	Mass and energy analysis of open systems, conservation of mass, flow work and energy of a flowing fluid	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 5
8	Midterm
9	Chemical kinetics and reaction mechanisms, reaction rate laws and stoichiometry	• Truskey, GA; Yuan, F; Katz, DF, ‘‘Transport Phenomena in Biological Systems (2nd Edition)’’, Pearson Prentice Hall Bioengineering, New Jersey, USA, 2010. Chapter 10 • H. Scott Fogler, ‘‘Elements of Chemical Reaction Engineering’’, 3rd Edition, Prentice Hall International, New Jersey, USA, 1999. Chapter 3
10	First order reactions, second order irreversible reactions, reversible reactions, material balances and mass transfer upon biochemical interactions.	• Truskey, GA; Yuan, F; Katz, DF, ‘‘Transport Phenomena in Biological Systems (2nd Edition)’’, Pearson Prentice Hall Bioengineering, New Jersey, USA, 2010. Chapter 10 • H. Scott Fogler, ‘‘Elements of Chemical Reaction Engineering’’, 3rd Edition, Prentice Hall International, New Jersey, USA, 1999. Chapter 3
11	Fundamentals of enzymatic reaction, enzyme kinetics, derivation of Michaelis-Menten kinetics	• Truskey, GA; Yuan, F; Katz, DF, ‘‘Transport Phenomena in Biological Systems (2nd Edition)’’, Pearson Prentice Hall Bioengineering, New Jersey, USA, 2010. Chapter 10 • H. Scott Fogler, ‘‘Elements of Chemical Reaction Engineering’’, 3rd Edition, Prentice Hall International, New Jersey, USA, 1999. Chapter 7
12	Chemical reaction thermodynamics	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 15
13	The second law of thermodynamics	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 6
14	The concept of entropy	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 7
15	Semester Review
16	Final Exam

Course Notes/Textbooks

Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. ISBN: 978-981-4595-29-2.

Suggested Readings/Materials

Truskey, GA; Yuan, F; Katz, DF, ‘‘Transport Phenomena in Biological Systems (2nd Edition)’’, Pearson Prentice Hall Bioengineering, New Jersey, USA, 2010. ISBN: 978-0130422040.

H. Scott Fogler, ‘‘Elements of Chemical Reaction Engineering’’, 3rd Edition, Prentice Hall International, New Jersey, USA, 1999. ISBN: 0-13-973785-5.

Semester Activities	Number	Weigthing	LO 1	LO 2	LO 3	LO 4	LO 5
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques	2	20
Portfolio
Homework / Assignments	1	15
Presentation / Jury
Project
Seminar / Workshop
Oral Exams
Midterm	1	25
Final Exam	1	40
Total

Weighting of Semester Activities on the Final Grade	4	60
Weighting of End-of-Semester Activities on the Final Grade	1	40
Total

Semester Activities	Number	Duration (Hours)	Workload
Theoretical Course Hours (Including exam week: 16 x total hours)	16	2	32
Laboratory / Application Hours (Including exam week: '.16.' x total hours)	16	2	32
Study Hours Out of Class	14	1	14
Field Work			0
Quizzes / Studio Critiques	2	12	24
Portfolio			0
Homework / Assignments	1	10	10
Presentation / Jury			0
Project			0
Seminar / Workshop			0
Oral Exam			0
Midterms	1	18	18
Final Exam	1	20	20
		Total	150

#	PC Sub	Program Competencies/Outcomes	* Contribution Level
#	PC Sub	Program Competencies/Outcomes	1	2	3	4	5
1	To have adequate knowledge in Mathematics, Science and Genetics and Bioengineering; to be able to use theoretical and applied information in these areas on complex engineering problems.		-	-	X	-	-
2	To be able to identify, define, formulate, and solve complex Genetics and Bioengineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.		-	-	-	X	-
3	To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.		-	X	-	-	-
4	To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Genetics and Bioengineering applications; to be able to use information technologies effectively.		-	-	-	-	-
5	To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Genetics and Bioengineering research topics.		-	-	-	-	-
6	To be able to work efficiently in Genetics and Bioengineering disciplinary and multi-disciplinary teams; to be able to work individually.		-	-	-	-	-
7	To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.		-	-	-	-	-
8	To have knowledge about global and social impact of Genetics and Bioengineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of Genetics and Bioengineering solutions.		-	-	-	-	-
9	To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in Genetics and Bioengineering applications.		-	-	-	-	-
10	To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.		-	-	-	-	-
11	To be able to collect data in the area of Genetics and Bioengineering, and to be able to communicate with colleagues in a foreign language.		-	-	-	-	-
12	To be able to speak a second foreign language at a medium level of fluency efficiently.		-	-	-	-	-
13	To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Genetics and Bioengineering.		-	-	-	-	-