FACULTY OF ENGINEERING

Department of Genetics and Bioengineering

GBE 310 | Course Introduction and Application Information

Course Name
Stem Cells
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
GBE 310
Fall/Spring
3
0
3
5

Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course Discussion
Group Work
Q&A
Lecture / Presentation
Course Coordinator
Course Lecturer(s)
Assistant(s) -
Course Objectives The aim of this course is tolearn fundamentals of stem cells, to be informed about the clinical applications of stem cells, and to discuss the role of stem cells in drug discovery.
Learning Outcomes The students who succeeded in this course;
  • Describe embryonic and induced pluripotent stem cells.
  • Explain the use of stem cells in cell therapy.
  • Define the use of stem cells in tissue engineering and drug discovery
  • Design a project on stem-cell based treatment of a disease
  • Critically discuss current literature and research papers on stem cells
Course Description Embryonic stem cells, Haematopoietic stem cells, Adult stem cells, tissue engineering, cell therapy, drug discovery.

 



Course Category

Core Courses
Major Area Courses
X
Supportive Courses
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Introduction to Stem Cells, Properties, Types and Stem Cell Niche Stem Cell Engineering
2 Human Embryonic and Induced Pluripotent Stem Cells Stem Cell Engineering
3 Genetic Modification of Human Embryonic and Induced Pluripotent Stem Cells Stem Cell Engineering-Chapter 7
4 Hematopoietic Stem Cells and The Therapeutic Potential of ES-Derived Haematopoietic Cells Stem Cell Engineering-Chapter 6
5 Mesenchymal Stem Cells Stem Cell Engineering
6 The Potential of Selectively Cultured Adult Stem Cells Re-implanted in Tissues Stem Cell Engineering-Chapter 4
7 The Immune Barriers of Cell Therapy with Allogenic Stem Cells of Embryonic Origin Stem Cell Engineering-Chapter 8
8 Midterm -
9 Tissue Engineering Stem Cell Engineering-Chapter 12
10 Endothelial Progenitor Cells for Vascular Repair Stem Cell Engineering-Chapter 13
11 Bio-synthetic Encapsulation Systems for Organ Engineering: Focus on Diabetes Stem Cell Engineering-Chapter 16
12 Adult Stem Cells in Drug Discovery Stem Cell Engineering-Chapter 21
13 Embryonic Stem Cells as a Tool for Drug Screening and Toxicity Testing Stem Cell Engineering-Chapter 22
14 Presentations -
15 Review
16 Final exam

 

Course Notes/Textbooks Stem Cell Engineering: Principlesand Applications,” EditorsArtmann, MingerandHescheler, Springer (2011).
Suggested Readings/Materials

Essentials of Stem Cell Biology – Robert Lanza, Anthony Atala - Elsevier 

Principles of Stem Cell Biology and Cancer – Future Applications and Therapeutic – Editors: Tarik Regad, Thomas J Sayers, Robert Rees – Wiley Blackwell 

Stem Cell Biology – Edited by Daniel R Marshak, Richard L Gardner, David Gottlieb – Cold Spring Harbor Laboratory Press 

Introduction to Stem Cell Science – Catherine Ennis, Emer Clarke, Cristopher Lannon, Eric Atkinson – Genetics Policy Institute

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
1
10
Portfolio
Homework / Assignments
Presentation / Jury
1
20
Project
1
20
Seminar / Workshop
Oral Exams
Midterm
1
20
Final Exam
1
30
Total

Weighting of Semester Activities on the Final Grade
5
70
Weighting of End-of-Semester Activities on the Final Grade
1
30
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: '.16.' x total hours)
16
0
Study Hours Out of Class
12
1
12
Field Work
0
Quizzes / Studio Critiques
1
5
5
Portfolio
0
Homework / Assignments
1
5
5
Presentation / Jury
1
10
10
Project
0
Seminar / Workshop
0
Oral Exam
0
Midterms
1
20
20
Final Exam
1
20
20
    Total
120

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

To have adequate knowledge in Mathematics, Science and Genetics and Bioengineering; to be able to use theoretical and applied information in these areas on complex engineering problems.

X
2

To be able to identify, define, formulate, and solve complex Genetics and Bioengineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.

3

To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.

X
4

To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Genetics and Bioengineering applications; to be able to use information technologies effectively.

5

To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Genetics and Bioengineering research topics.

6

To be able to work efficiently in Genetics and Bioengineering disciplinary and multi-disciplinary teams; to be able to work individually.

X
7

To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.

8

To have knowledge about global and social impact of Genetics and Bioengineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of Genetics and Bioengineering solutions.

9

To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in Genetics and Bioengineering applications.

10

To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.

11

To be able to collect data in the area of Genetics and Bioengineering, and to be able to communicate with colleagues in a foreign language.

12

To be able to speak a second foreign language at a medium level of fluency efficiently.

13

To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Genetics and Bioengineering.

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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