FACULTY OF ENGINEERING

Department of Genetics and Bioengineering

GBE 370 | Course Introduction and Application Information

Course Name
Molecular Immunology
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
GBE 370
Fall/Spring
3
0
3
6

Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course Discussion
Group Work
Q&A
Lecture / Presentation
Course Coordinator
Course Lecturer(s)
Assistant(s) -
Course Objectives The objective of this course is to teach the cells and tissues that comprise the immune system and the differences between innate and adaptive immunity. Also, it aims to explain the selection, tolerance, memory mechanisms of immune system and relationships between immunity and diseases. This course, according to genetics and bioengineering based studies, will provide important background knowledge especially on the topics of immune system mechanisms and their effect on disease durations.\n
Learning Outcomes The students who succeeded in this course;
  • Classify cells, receptors and molecules that are part of the immune system,
  • Discuss the key features of innate and adaptive immunity,
  • Explain the concept of B cell development and function, antibody formation, structure and effector function together with T cell development and function, cytokines and their essential functions, and effects on the immune system
  • Describe the basic concepts of antigen presentation and structure and function of antigen-presenting molecules,
  • Explain tumor immunity, autoimmunity and immunity to viruses and how immunity relates to diseases, design a research project on immunotherapy;
  • Discuss immunology-related research articles.
Course Description This course will include discussion of the properties of innate and adaptive immunity, the cells of the immune system. Additionally, students will learn about antibody structure and function, antigen recognition, lymphocyte activation, and immunity to microbes. Immunity that relates to diseases will also be covered including autoimmunity, transplantation, immunity to viruses and tumor immunology.

 



Course Category

Core Courses
Major Area Courses
X
Supportive Courses
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Introduction to Immune System, Cells of the Immune System & Lymphoid Organs Janeway’s Immunobiology 9th Edition, Part I
2 Innate Immunity Janeway’s Immunobiology 9th Edition, Part I
3 Adaptive Immunity Janeway’s Immunobiology 9th Edition, Part IV
4 B-Cells and Antibodies / Antibody Classes & Functions Janeway’s Immunobiology 9th Edition, Part II
5 Antigen Presentation / MHC Classes Janeway’s Immunobiology 9th Edition, Part II
6 T-Cell Activation and Signaling Janeway’s Immunobiology 9th Edition, Part IV
7 T-Cell Receptors, Response Janeway’s Immunobiology 9th Edition, Part IV
8 Midterm
9 Autoimmunity Janeway’s Immunobiology 9th Edition, Part V
10 Tumor Immunology / Immunotherapy Janeway’s Immunobiology 9th Edition, Part V
11 Transplantation Janeway’s Immunobiology 9th Edition, Part V
12 Immunity to Viruses / Vaccinology Janeway’s Immunobiology 9th Edition, Part V
13 Research Paper Presentations TBD
14 Research Paper Presentations TBD
15 Review
16 Final Exam

 

Course Notes/Textbooks

Janeway’s Immunobiology 9th Edition, Kenneth Murphy & Casey Weaver 2016, Garland Science
ISBN-13: 9781315533247 ISBN: 1315533243

Suggested Readings/Materials

Kuby Immunology by Kindt, Goldsby and Osborne, 2007, W.H. Freeman and Company, New York, NY

Primary journals:
Vaccine, 
Immunology, 
Journal of Immunology, 
Infection and Immunity, 
Nature Reviews Immunology,
Frontiers in Immunology.

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
2
10
Portfolio
Homework / Assignments
1
5
Presentation / Jury
1
15
Project
1
20
Seminar / Workshop
Oral Exams
Midterm
1
20
Final Exam
1
30
Total

Weighting of Semester Activities on the Final Grade
6
70
Weighting of End-of-Semester Activities on the Final Grade
1
30
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: '.16.' x total hours)
16
0
Study Hours Out of Class
14
2
28
Field Work
0
Quizzes / Studio Critiques
2
5
10
Portfolio
0
Homework / Assignments
1
10
10
Presentation / Jury
1
20
20
Project
0
Seminar / Workshop
0
Oral Exam
0
Midterms
1
20
20
Final Exam
1
24
24
    Total
160

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

To have adequate knowledge in Mathematics, Science and Genetics and Bioengineering; to be able to use theoretical and applied information in these areas on complex engineering problems.

X
2

To be able to identify, define, formulate, and solve complex Genetics and Bioengineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.

3

To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.

X
4

To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Genetics and Bioengineering applications; to be able to use information technologies effectively.

5

To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Genetics and Bioengineering research topics.

6

To be able to work efficiently in Genetics and Bioengineering disciplinary and multi-disciplinary teams; to be able to work individually.

X
7

To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.

8

To have knowledge about global and social impact of Genetics and Bioengineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of Genetics and Bioengineering solutions.

9

To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in Genetics and Bioengineering applications.

10

To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.

11

To be able to collect data in the area of Genetics and Bioengineering, and to be able to communicate with colleagues in a foreign language.

12

To be able to speak a second foreign language at a medium level of fluency efficiently.

13

To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Genetics and Bioengineering.

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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