FACULTY OF ENGINEERING

Department of Genetics and Bioengineering

GBE 405 | Course Introduction and Application Information

Course Name
Transgenic Organisms
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
GBE 405
Fall/Spring
3
0
3
5

Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course Discussion
Group Work
Q&A
Lecture / Presentation
Course Coordinator
Course Lecturer(s)
Assistant(s) -
Course Objectives The aim of this course is to give information on techniques and technologies used in production of transgenic organisms, and use of these transgenic organisms for industrial and research purposes.
Learning Outcomes The students who succeeded in this course;
  • Define basics of recombinant DNA techniques
  • Explain how transgenic organisms are produced
  • Explain CRISPR/Cas9 system in gene editing
  • Utilize genetic techniques to create genetically modified organisms
  • Decide which genetic methods are available and of best suitability regarding to the organism intended to be genetically modified.
Course Description Recombinant DNA methods, genetically modified plants and animals and their use

 



Course Category

Core Courses
Major Area Courses
X
Supportive Courses
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Introduction to transgenic organisms
2 General concepts Transgenic Animal Technology, 3rd Edition - Chapter 1
3 DNA microinjection Transgenic Animal Technology, 3rd Edition - Chapter 2
4 Retrovirus-mediated gene transfer Transgenic Animal Technology, 3rd Editionk - Chapter 6
5 Nuclear transfer technologies Transgenic Animal Technology, 3rd Edition- Chapter7
6 Gene editing
7 1.Midterm
8 Analysis of phenotype Transgenic Animal Technology, 3rd Edition - Chapter16
9 Design of vectors for optimizing transgene expression Transgenic Animal Technology, 3rd Edition - Chapter17, 18
10 Analysis of transgene Transgenic Animal Technology, 3rd Edition - Chapter18, 19, 20
11 Analysis of transgene Transgenic Animal Technology, 3rd Edition-Chapter18, 19, 20
12 2.Midterm
13 Production of transgenicanimals Transgenic Animal Technology, 3rd Edition – Section III
14 Production of transgenic plants Related Articles
15 Review
16 Final exam

 

Course Notes/Textbooks Pinkert C. Transgenic Animal Technology, 3rd Edition. A Laboratory Handbook. Elsevier 2014.
Suggested Readings/Materials

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
1
10
Portfolio
Homework / Assignments
2
20
Presentation / Jury
1
10
Project
Seminar / Workshop
Oral Exams
Midterm
1
30
Final Exam
2
30
Total

Weighting of Semester Activities on the Final Grade
6
70
Weighting of End-of-Semester Activities on the Final Grade
1
30
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: '.16.' x total hours)
16
0
Study Hours Out of Class
0
Field Work
0
Quizzes / Studio Critiques
1
16
16
Portfolio
0
Homework / Assignments
2
15
30
Presentation / Jury
1
12
12
Project
1
13
13
Seminar / Workshop
0
Oral Exam
0
Midterms
1
15
15
Final Exam
2
8
16
    Total
150

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

To have adequate knowledge in Mathematics, Science and Genetics and Bioengineering; to be able to use theoretical and applied information in these areas on complex engineering problems.

2

To be able to identify, define, formulate, and solve complex Genetics and Bioengineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.

X
3

To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.

4

To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Genetics and Bioengineering applications; to be able to use information technologies effectively.

X
5

To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Genetics and Bioengineering research topics.

6

To be able to work efficiently in Genetics and Bioengineering disciplinary and multi-disciplinary teams; to be able to work individually.

X
7

To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.

8

To have knowledge about global and social impact of Genetics and Bioengineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of Genetics and Bioengineering solutions.

9

To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in Genetics and Bioengineering applications.

X
10

To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.

11

To be able to collect data in the area of Genetics and Bioengineering, and to be able to communicate with colleagues in a foreign language.

12

To be able to speak a second foreign language at a medium level of fluency efficiently.

13

To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Genetics and Bioengineering.

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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