FACULTY OF ENGINEERING

Department of Genetics and Bioengineering

MED 260 | Course Introduction and Application Information

Course Name
Introduction to Immunology
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
MED 260
Fall/Spring
3
0
3
4

Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course -
Course Coordinator
Course Lecturer(s) -
Assistant(s) -
Course Objectives This course aims to train the students with an introductory level in immunology.
Learning Outcomes The students who succeeded in this course;
  • 1-Define basic immunology concepts and terms.
  • 2-Describe the cells, tissues and organs related to immunology.
  • 3-Specify the stages of immune response and signs of inflammation.
  • 4-Explain natural and acquired immunity, related cells and antigen presentation.
  • 5-Classify the main disease groups associated with the dysregulation of the immune system.
  • 6-Explain examples of cancer-specific immune responses and their use in cancer treatment.
Course Description This course begins with a general introduction to how immune system cells and tissues work, followed by the development and migration of these cells under physiological conditions. The course will continue with the stages of immune response and inflammation under pathological conditions, and will focus on the basic mechanisms of immune responses.

 



Course Category

Core Courses
Major Area Courses
Supportive Courses
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Introduction Examination of the posted syllabus, requirements and course flow
2 Immune system Cells and Tissues: Myeloid vs. Lymphoid Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 1 and 2 p 1-35
3 Development and Migration of Leukocytes Janeway C. and Medzhitov R. Immunobiology 8th Ed. Ch. 1
4 Phases of an Immune response and Inflammation Sherris Medical Microbiology Kenneth C. Ryan Chapter 2: Immune response to Infection. Innate (Natural) Immunity (Access Medicine- no page numbers)
5 Innate immune system: Mucosal Immunity and Microbiota “The human skin microbiome” Nature Reviews Microbiology 16, pages 143–155 (2018) doi:10.1038/nrmicro.2017.157 Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 14 p 289
6 Innate immune system: Phagocytosis and Complement system Jawetz Medical Microbiology Chapter 8: Immunity: Mechanisms of Innate Immunity: Innate (Natural) Immunity D. Complement System (Access Medicine- no page numbers)
7 Antigens and Antigen presentation Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 6 p 117-145
8 T lymphocytes and activation Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 8, 9, 10 and11 p 171-239
9 B lymphocytes and activation, antibody production and function Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 8, 12 and 13 p 239-289
10 Tolerance and Autoimmunity: Case study Review of Medical Microbiology & Immunology: A Guide to Clinical Infectious Diseases, 16e Chap 38: Respiratory viruses
11 Hypersensitivity and Allergy Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 19-20 p 417-437
12 Immunodeficiencies and Transplantation Immunology Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 17-21 p 373/459
13 Tumor Immunology and Immunotherapy of Cancer Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 18 p 397-417 Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice, Section II: Cancer Immunothrapy Targets and Classes 231-404
14 Immunotherapy of Cancer Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice, Section II: Cancer Immunothrapy Targets and Classes 231-404
15 Poster presentations and Semester Review
16 Final Exam

 

Course Notes/Textbooks

Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy ISBN 9781620700976

Abul K Abbas, Andrew H Lichtman, Shiv Pillai, “Cellular and Molecular Immunology” 8th Edition ISBN 978-0 323-52324-0

Karren C Carroll, Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e 2018 ISBN 9780-0-71-82498-9

Kenneth J Ryan, Sherris Medical Microbiology 7th ed. 2018 ISBN 978-1-259-85980-9

Charles Janeway and Ruslan Medzhitov “Immunobiology” 9th Ed. ISBN 978-0815345848

Suggested Readings/Materials

Access Medicine online access to  Jawetz Medical Microbiology

Sherris Medical Microbiology will be provided by the Faculty of Medicine online acccess

Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition is available through IEU library

Notes from Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice will be provided during the course

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
1
10
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
1
10
Presentation / Jury
1
40
Project
Seminar / Workshop
Oral Exams
Midterm
Final Exam
1
40
Total

Weighting of Semester Activities on the Final Grade
3
60
Weighting of End-of-Semester Activities on the Final Grade
1
40
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: '.16.' x total hours)
16
0
Study Hours Out of Class
15
2
30
Field Work
0
Quizzes / Studio Critiques
0
Portfolio
0
Homework / Assignments
1
10
10
Presentation / Jury
1
10
10
Project
0
Seminar / Workshop
0
Oral Exam
0
Midterms
0
Final Exam
1
22
22
    Total
120

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

To have adequate knowledge in Mathematics, Science and Genetics and Bioengineering; to be able to use theoretical and applied information in these areas on complex engineering problems.

2

To be able to identify, define, formulate, and solve complex Genetics and Bioengineering problems; to be able to select and apply proper analysis and modeling methods for this purpose.

3

To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose.

4

To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Genetics and Bioengineering applications; to be able to use information technologies effectively.

5

To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Genetics and Bioengineering research topics.

6

To be able to work efficiently in Genetics and Bioengineering disciplinary and multi-disciplinary teams; to be able to work individually.

7

To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions.

8

To have knowledge about global and social impact of Genetics and Bioengineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of Genetics and Bioengineering solutions.

9

To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in Genetics and Bioengineering applications.

10

To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development.

11

To be able to collect data in the area of Genetics and Bioengineering, and to be able to communicate with colleagues in a foreign language.

12

To be able to speak a second foreign language at a medium level of fluency efficiently.

13

To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Genetics and Bioengineering.

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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