FACULTY OF ENGINEERING
Department of Genetics and Bioengineering
MED 260 | Course Introduction and Application Information
Course Name |
Introduction to Immunology
|
Code
|
Semester
|
Theory
(hour/week) |
Application/Lab
(hour/week) |
Local Credits
|
ECTS
|
MED 260
|
Fall/Spring
|
3
|
0
|
3
|
4
|
Prerequisites |
None
|
|||||
Course Language |
English
|
|||||
Course Type |
Elective
|
|||||
Course Level |
First Cycle
|
|||||
Mode of Delivery | - | |||||
Teaching Methods and Techniques of the Course | - | |||||
Course Coordinator | ||||||
Course Lecturer(s) | - | |||||
Assistant(s) | - |
Course Objectives | This course aims to train the students with an introductory level in immunology. |
Learning Outcomes |
The students who succeeded in this course;
|
Course Description | This course begins with a general introduction to how immune system cells and tissues work, followed by the development and migration of these cells under physiological conditions. The course will continue with the stages of immune response and inflammation under pathological conditions, and will focus on the basic mechanisms of immune responses. |
|
Core Courses | |
Major Area Courses | ||
Supportive Courses | ||
Media and Management Skills Courses | ||
Transferable Skill Courses |
WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES
Week | Subjects | Related Preparation |
1 | Introduction | Examination of the posted syllabus, requirements and course flow |
2 | Immune system Cells and Tissues: Myeloid vs. Lymphoid | Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 1 and 2 p 1-35 |
3 | Development and Migration of Leukocytes | Janeway C. and Medzhitov R. Immunobiology 8th Ed. Ch. 1 |
4 | Phases of an Immune response and Inflammation | Sherris Medical Microbiology Kenneth C. Ryan Chapter 2: Immune response to Infection. Innate (Natural) Immunity (Access Medicine- no page numbers) |
5 | Innate immune system: Mucosal Immunity and Microbiota | “The human skin microbiome” Nature Reviews Microbiology 16, pages 143–155 (2018) doi:10.1038/nrmicro.2017.157 Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 14 p 289 |
6 | Innate immune system: Phagocytosis and Complement system | Jawetz Medical Microbiology Chapter 8: Immunity: Mechanisms of Innate Immunity: Innate (Natural) Immunity D. Complement System (Access Medicine- no page numbers) |
7 | Antigens and Antigen presentation | Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 6 p 117-145 |
8 | T lymphocytes and activation | Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 8, 9, 10 and11 p 171-239 |
9 | B lymphocytes and activation, antibody production and function | Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 8, 12 and 13 p 239-289 |
10 | Tolerance and Autoimmunity: Case study | Review of Medical Microbiology & Immunology: A Guide to Clinical Infectious Diseases, 16e Chap 38: Respiratory viruses |
11 | Hypersensitivity and Allergy | Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 19-20 p 417-437 |
12 | Immunodeficiencies and Transplantation Immunology | Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 17-21 p 373/459 |
13 | Tumor Immunology and Immunotherapy of Cancer | Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 18 p 397-417 Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice, Section II: Cancer Immunothrapy Targets and Classes 231-404 |
14 | Immunotherapy of Cancer | Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice, Section II: Cancer Immunothrapy Targets and Classes 231-404 |
15 | Poster presentations and Semester Review | |
16 | Final Exam |
Course Notes/Textbooks | Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy ISBN 9781620700976 Abul K Abbas, Andrew H Lichtman, Shiv Pillai, “Cellular and Molecular Immunology” 8th Edition ISBN 978-0 323-52324-0 Karren C Carroll, Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e 2018 ISBN 9780-0-71-82498-9 Kenneth J Ryan, Sherris Medical Microbiology 7th ed. 2018 ISBN 978-1-259-85980-9 Charles Janeway and Ruslan Medzhitov “Immunobiology” 9th Ed. ISBN 978-0815345848 |
Suggested Readings/Materials | Access Medicine online access to Jawetz Medical Microbiology Sherris Medical Microbiology will be provided by the Faculty of Medicine online acccess Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition is available through IEU library Notes from Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice will be provided during the course |
EVALUATION SYSTEM
Semester Activities | Number | Weigthing |
Participation |
1
|
10
|
Laboratory / Application | ||
Field Work | ||
Quizzes / Studio Critiques | ||
Portfolio | ||
Homework / Assignments |
1
|
10
|
Presentation / Jury |
1
|
40
|
Project | ||
Seminar / Workshop | ||
Oral Exams | ||
Midterm | ||
Final Exam |
1
|
40
|
Total |
Weighting of Semester Activities on the Final Grade |
3
|
60
|
Weighting of End-of-Semester Activities on the Final Grade |
1
|
40
|
Total |
ECTS / WORKLOAD TABLE
Semester Activities | Number | Duration (Hours) | Workload |
---|---|---|---|
Theoretical Course Hours (Including exam week: 16 x total hours) |
16
|
3
|
48
|
Laboratory / Application Hours (Including exam week: '.16.' x total hours) |
16
|
0
|
|
Study Hours Out of Class |
15
|
2
|
30
|
Field Work |
0
|
||
Quizzes / Studio Critiques |
0
|
||
Portfolio |
0
|
||
Homework / Assignments |
1
|
10
|
10
|
Presentation / Jury |
1
|
10
|
10
|
Project |
0
|
||
Seminar / Workshop |
0
|
||
Oral Exam |
0
|
||
Midterms |
0
|
||
Final Exam |
1
|
22
|
22
|
Total |
120
|
COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP
#
|
Program Competencies/Outcomes |
* Contribution Level
|
||||
1
|
2
|
3
|
4
|
5
|
||
1 | To have adequate knowledge in Mathematics, Science and Genetics and Bioengineering; to be able to use theoretical and applied information in these areas on complex engineering problems. |
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2 | To be able to identify, define, formulate, and solve complex Genetics and Bioengineering problems; to be able to select and apply proper analysis and modeling methods for this purpose. |
|||||
3 | To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose. |
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4 | To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Genetics and Bioengineering applications; to be able to use information technologies effectively. |
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5 | To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Genetics and Bioengineering research topics. |
|||||
6 | To be able to work efficiently in Genetics and Bioengineering disciplinary and multi-disciplinary teams; to be able to work individually. |
|||||
7 | To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions. |
|||||
8 | To have knowledge about global and social impact of Genetics and Bioengineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of Genetics and Bioengineering solutions. |
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9 | To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in Genetics and Bioengineering applications. |
|||||
10 | To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development. |
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11 | To be able to collect data in the area of Genetics and Bioengineering, and to be able to communicate with colleagues in a foreign language. |
|||||
12 | To be able to speak a second foreign language at a medium level of fluency efficiently. |
|||||
13 | To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Genetics and Bioengineering. |
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest
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