FACULTY OF ENGINEERING
Department of Genetics and Bioengineering
MED 310 | Course Introduction and Application Information
Course Name |
Current Topics in Immunology and Cancer
|
Code
|
Semester
|
Theory
(hour/week) |
Application/Lab
(hour/week) |
Local Credits
|
ECTS
|
MED 310
|
Fall/Spring
|
3
|
0
|
3
|
5
|
Prerequisites |
None
|
|||||
Course Language |
English
|
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Course Type |
Elective
|
|||||
Course Level |
First Cycle
|
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Mode of Delivery | - | |||||
Teaching Methods and Techniques of the Course | DiscussionGroup WorkJuryLecture / Presentation | |||||
Course Coordinator | ||||||
Course Lecturer(s) | ||||||
Assistant(s) | - |
Course Objectives | This course aims to inform students about the latest topics in immunology by focusing on cancer. |
Learning Outcomes |
The students who succeeded in this course;
|
Course Description | This course begins with a general introduction to the mechanism of antigen delivery, which is a summary of the innate and adaptive immune system, which aims to cover the functioning of the immune system cells and tissues and then the basic mechanisms of the immune system as a whole. The course will focus on the main mechanisms of tumor immune response and its therapy. |
|
Core Courses | |
Major Area Courses | ||
Supportive Courses | ||
Media and Management Skills Courses | ||
Transferable Skill Courses |
WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES
Week | Subjects | Related Preparation |
1 | Introduction to the Immune system: Cells and Tissues of the Immune System | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 1, 1-11 Chapter 2, 13-41 |
2 | Antigen Presentation to T Lymphocytes and the Function of Major Histocompatibility Complex Molecules | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 6, 123-150 |
3 | Innate Immune System | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 4, 63-102 |
4 | Activation of T lymphocytes, Differentiation and Function of CD4 and CD8 T Cells | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 9, 217-232 Chapter 10, 233-250 Chapter 11, 251-259 |
5 | B Cell Activation and Antibody production | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 12, 261-285 |
6 | Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 14, 313-336 |
7 | Transplantation Immunology | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 17, 389-413 |
8 | Immune Tolerance and Autoimmunity | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 15, 337-363 |
9 | Immune Regulation | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 9 and 15 p 211-213, 315-339 |
10 | Tumor Antigens | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com |
11 | Tumor Immune Responses | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com |
12 | Evasion of Immune Responses by Tumors | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com |
13 | Immunotherapy for Tumors I: Passive Immunotherapy and Adoptive T Cell Therapy | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com |
14 | Immunotherapy for Tumors II: Immune Checkpoint Blockade and Tumor Antigen Vaccination | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com |
15 | Semester Review | |
16 | Final Exam |
Course Notes/Textbooks | Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD
Access through www.clinicalkey.com |
Suggested Readings/Materials |
EVALUATION SYSTEM
Semester Activities | Number | Weigthing |
Participation |
1
|
10
|
Laboratory / Application | ||
Field Work | ||
Quizzes / Studio Critiques | ||
Portfolio | ||
Homework / Assignments |
1
|
20
|
Presentation / Jury |
1
|
30
|
Project | ||
Seminar / Workshop | ||
Oral Exams | ||
Midterm | ||
Final Exam |
1
|
40
|
Total |
Weighting of Semester Activities on the Final Grade |
3
|
60
|
Weighting of End-of-Semester Activities on the Final Grade |
1
|
40
|
Total |
ECTS / WORKLOAD TABLE
Semester Activities | Number | Duration (Hours) | Workload |
---|---|---|---|
Theoretical Course Hours (Including exam week: 16 x total hours) |
16
|
3
|
48
|
Laboratory / Application Hours (Including exam week: '.16.' x total hours) |
16
|
0
|
|
Study Hours Out of Class |
14
|
2
|
28
|
Field Work |
0
|
||
Quizzes / Studio Critiques |
0
|
||
Portfolio |
0
|
||
Homework / Assignments |
1
|
15
|
15
|
Presentation / Jury |
1
|
25
|
25
|
Project |
0
|
||
Seminar / Workshop |
0
|
||
Oral Exam |
0
|
||
Midterms |
0
|
||
Final Exam |
1
|
24
|
24
|
Total |
140
|
COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP
#
|
Program Competencies/Outcomes |
* Contribution Level
|
||||
1
|
2
|
3
|
4
|
5
|
||
1 | To have adequate knowledge in Mathematics, Science and Genetics and Bioengineering; to be able to use theoretical and applied information in these areas on complex engineering problems. |
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2 | To be able to identify, define, formulate, and solve complex Genetics and Bioengineering problems; to be able to select and apply proper analysis and modeling methods for this purpose. |
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3 | To be able to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the requirements; to be able to apply modern design methods for this purpose. |
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4 | To be able to devise, select, and use modern techniques and tools needed for analysis and solution of complex problems in Genetics and Bioengineering applications; to be able to use information technologies effectively. |
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5 | To be able to design and conduct experiments, gather data, analyze and interpret results for investigating complex engineering problems or Genetics and Bioengineering research topics. |
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6 | To be able to work efficiently in Genetics and Bioengineering disciplinary and multi-disciplinary teams; to be able to work individually. |
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7 | To be able to communicate effectively in Turkish, both orally and in writing; to be able to author and comprehend written reports, to be able to prepare design and implementation reports, to present effectively, to be able to give and receive clear and comprehensible instructions. |
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8 | To have knowledge about global and social impact of Genetics and Bioengineering practices on health, environment, and safety; to have knowledge about contemporary issues as they pertain to engineering; to be aware of the legal ramifications of Genetics and Bioengineering solutions. |
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9 | To be aware of ethical behavior, professional and ethical responsibility; to have knowledge about standards utilized in Genetics and Bioengineering applications. |
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10 | To have knowledge about industrial practices such as project management, risk management, and change management; to have awareness of entrepreneurship and innovation; to have knowledge about sustainable development. |
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11 | To be able to collect data in the area of Genetics and Bioengineering, and to be able to communicate with colleagues in a foreign language. |
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12 | To be able to speak a second foreign language at a medium level of fluency efficiently. |
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13 | To recognize the need for lifelong learning; to be able to access information, to be able to stay current with developments in science and technology; to be able to relate the knowledge accumulated throughout the human history to Genetics and Bioengineering. |
*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest
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