Department of Genetics and Bioengineering

GBE 214 | Course Introduction and Application Information

Course Name

Thermodynamics and Kinetics

Code	Semester	Theory (hour/week)	Application/Lab (hour/week)	Local Credits	ECTS
GBE 214	SPRING	2	2	3	6

Prerequisites	None
Course Language	English
Course Type	Required (Core Course)
Course Level	First Cycle
Mode of Delivery	Face to Face
Teaching Methods and Techniques of the Course	Discussion Problem Solving Q&A Lecture / Presentation
National Occupational Classification Code	-
Course Coordinator	Dr. Öğr. Üyesi Işınay Ebru Yüzay
Course Lecturer(s)	Dr. Öğr. Üyesi Işınay Ebru Yüzay
Assistant(s)	Araş. Gör. Recep Yılmaz

Course Objectives

The objective of this course is to teach the basic concepts and laws of thermodynamics and the basic principles of reaction kinetics and to explain their applications in bioengineering.

Learning Outcomes

The students who succeeded in this course;

Name	Description	PC Sub	* Contribution Level
Name	Description	PC Sub	1	2	3	4	5
LO1	Define the basic concepts and laws of thermodynamics,	1.3			X
LO2	Use property tables and equations of state in the evaluation of thermodynamic properties,	2			X
LO3	Apply mass and energy balances, and the first law of thermodynamics in the solution of engineering problems,	1.6			X
LO4	Determine the rate and order of a reaction,	2				X
LO5	Explain the applications of thermodynamic laws and reaction kinetics in bioengineering.	3.2		X

Course Description

This course covers energy forms, thermodynamic laws, property tables, equations of state, internal energy, specific heat, enthalpy, conservation of mass and energy, reaction kinetics and mechanisms, entropy and free energy concepts, and applications of thermodynamic laws and reaction kinetics in bioengineering.

Related Sustainable Development Goals

Course Category	Core Courses	X
	Major Area Courses
	Supportive Courses
	Media and Managment Skills Courses
	Transferable Skill Courses

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week	Subjects	Required Materials	Learning Outcome
1	Introduction to thermodynamics and basic concepts	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 1	LO1
2	Forms of energy and energy transfer by heat and work, general concepts of bio-heat transfer	•Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 2 Truskey, GA; Yuan, F; Katz, DF, ‘‘Transport Phenomena in Biological Systems (2nd Edition)’’, Pearson Prentice Hall Bioengineering, New Jersey, USA, 2010. Chapter 17	LO1
3	The first law of thermodynamics, conservation and conversion of energy	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 2	LO1
4	Properties of pure substances, phase-change processes	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 3	LO2
5	Property tables and equations of state	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 3	LO2
6	Energy analysis of closed systems, internal energy, enthalpy and specific heat	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 4	LO2
7	Mass and energy analysis of open systems, conservation of mass, flow work and energy of a flowing fluid	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 5	LO3
8	Midterm		-
9	Chemical kinetics and reaction mechanisms, reaction rate laws and stoichiometry	Truskey, GA; Yuan, F; Katz, DF, ‘‘Transport Phenomena in Biological Systems (2nd Edition)’’, Pearson Prentice Hall Bioengineering, New Jersey, USA, 2010. Chapter 10 H. Scott Fogler, ‘‘Elements of Chemical Reaction Engineering’’, 3rd Edition, Prentice Hall International, New Jersey, USA, 1999. Chapter 3	LO4
10	First order reactions, second order irreversible reactions, reversible reactions, material balances and mass transfer upon biochemical interactions	Truskey, GA; Yuan, F; Katz, DF, ‘‘Transport Phenomena in Biological Systems (2nd Edition)’’, Pearson Prentice Hall Bioengineering, New Jersey, USA, 2010. Chapter 10 H. Scott Fogler, ‘‘Elements of Chemical Reaction Engineering’’, 3rd Edition, Prentice Hall International, New Jersey, USA, 1999. Chapter 3	LO4
11	Fundamentals of enzymatic reaction, enzyme kinetics, derivation of Michaelis-Menten kinetics	Truskey, GA; Yuan, F; Katz, DF, ‘‘Transport Phenomena in Biological Systems (2nd Edition)’’, Pearson Prentice Hall Bioengineering, New Jersey, USA, 2010. Chapter 10 H. Scott Fogler, ‘‘Elements of Chemical Reaction Engineering’’, 3rd Edition, Prentice Hall International, New Jersey, USA, 1999. Chapter 7	LO5
12	Chemical reaction thermodynamics	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 15	LO5
13	The second law of thermodynamics	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 6	LO5
14	The concept of entropy	Çengel, YA; Boles, MA, “Thermodynamics: An Engineering Approach (8th Edition in SI Units)”, McGraw-Hill Education, New York, USA, 2015. Chapter 7	LO1
15	Semester Review		-
16	Final Exam		-

Course Notes/Textbooks	Çengel YA; Boles MA. “Thermodynamics: An Engineering Approach (8th Edition in SI Units)” McGraw-Hill Education New York USA 2015.
Suggested Readings/Materials	-

EVALUATION SYSTEM

Semester Activities	Number	Weighting	LO1	LO2	LO3	LO4	LO5
Quizzes / Studio Critiques	2	20	X	X	X	X
Homework / Assignments	1	15					X
Midterm	1	25	X	X	X
Final Exam	1	40	X		X	X	X
Total	5	100

ECTS / WORKLOAD TABLE

Semester Activities	Number	Duration (Hours)	Workload
Participation	-	-	-
Theoretical Course Hours	16	2	32
Laboratory / Application Hours	16	2	32
Study Hours Out of Class	14	2	28
Field Work	-	-	-
Quizzes / Studio Critiques	2	12	24
Portfolio	-	-	-
Homework / Assignments	1	15	15
Presentation / Jury	-	-	-
Project	-	-	-
Seminar / Workshop	-	-	-
Oral Exams	-	-	-
Midterms	1	22	22
Final Exam	1	27	27
		Total	180

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#	PC Sub	Program Competencies/Outcomes	* Contribution Level
#	PC Sub	Program Competencies/Outcomes	1	2	3	4	5
1	Engineering Knowledge: Knowledge of mathematics, science, basic engineering, computation, and related engineering discipline-specific topics; the ability to apply this knowledge to solve complex engineering problems.
	1	Mathematics
	2	Science
	3	Basic Engineering			LO1
	4	Computation
	5	Related engineering discipline-specific topics
	6	The ability to apply this knowledge to solve complex engineering problems			LO3
2	Problem Analysis: Ability to identify, formulate and analyze complex engineering problems using basic knowledge of science, mathematics and engineering, and considering the UN Sustainable Development Goals relevant to the problem being addressed.				LO2	LO4
3	Engineering Design: The ability to devise creative solutions to complex engineering problems; the ability to design complex systems, processes, devices or products to meet current and future needs, considering realistic constraints and conditions.
	1	Ability to design creative solutions to complex engineering problems
	2	Ability to design complex systems, processes, devices or products to meet current and future needs, considering realistic constraints and conditions		LO5
4	Use of Techniques and Tools: Ability to select and use appropriate techniques, resources, and modern engineering and computing tools, including estimation and modeling, for the analysis and solution of complex engineering problems, while recognizing their limitations.
5	Research and Investigation: Ability to use research methods to investigate complex engineering problems, including literature research, designing and conducting experiments, collecting data, and analyzing and interpreting results.
	1	Literature research for the study of complex engineering problems
	2	Designing experiments
	3	Ability to use research methods, including conducting experiments, collecting data. analyzing and interpreting results
6	Global Impact of Engineering Practices: Knowledge of the impacts of engineering practices on society, health and safety, economy, sustainability, and the environment, within the context of the UN Sustainable Development Goals; awareness of the legal implications of engineering solutions.
	1	Knowledge of the impacts of engineering practices on society, health and safety, economy, sustainability, and the environment, within the context of the UN Sustainable Development Goals
	2	Awareness of the legal implications of engineering solutions
7	Ethical Behavior: Acting in accordance with the principles of the engineering profession, knowledge about ethical responsibility; awareness of being impartial, without discrimination, and being inclusive of diversity.
	1	Acting in accordance with the principles of the engineering profession, knowledge about ethical responsibility ethical responsibility
	2	Awareness of being impartial and inclusive of diversity, without discriminating on any subject
8	Individual and Teamwork: Ability to work effectively, individually and as a team member or leader on interdisciplinary and multidisciplinary teams (face-to-face, remote or hybrid).
	1	Ability to work individually and within the discipline
	2	Ability to work effectively as a team member or leader in multidisciplinary teams (face-to-face, remote or hybrid)
9	Verbal and Written Communication: Taking into account the various differences of the target audience (such as education, language, profession) on technical issues.
	1	Ability to communicate verbally
	2	Ability to communicate effectively in writing
10	Project Management: Knowledge of business practices such as project management and economic feasibility analysis; awareness of entrepreneurship and innovation.
	1	Knowledge of business practices such as project management and economic feasibility analysis
	2	Awareness of entrepreneurship and innovation
11	Lifelong Learning: Lifelong learning skills that include being able to learn independently and continuously, adapting to new and developing technologies, and thinking questioningly about technological changes.