Genetik ve Biyomühendislik

GBE 407 | Ders Tanıtım Bilgileri

Dersin Adı

Genomics and Proteomics

Kodu	Yarıyıl	Teori (saat/hafta)	Uygulama/Lab (saat/hafta)	Yerel Kredi	AKTS
GBE 407	SPRING	2	2	3	6

Ön-Koşul(lar)	Yok
Dersin Dili	English
Dersin Türü	ELECTIVE_COURSE
Dersin Düzeyi	Lisans
Dersin Veriliş Şekli	Face to Face
Dersin Öğretim Yöntem ve Teknikleri	Discussion Group Work Q&A Lecture / Presentation
Ulusal Meslek Sınıflandırma Kodu	-
Dersin Koordinatörü	Doç. Dr. Osman Doluca
Öğretim Eleman(lar)ı	Doç. Dr. Osman Doluca
Yardımcı(ları)	-

Dersin Amacı

The aim of this course is to introduce the methods which are used in protein biochemistry, bioinformatics and functional genomics In the scope of this lecture, responses of eukaryotic organisms to biotic and abiotic stress in all genome levels will be analyzed and the importance of personalized drug applications will be discussed.

Öğrenme Çıktıları

Bu dersi başarıyla tamamlayabilen öğrenciler;

Ad	Açıklama	PC Alt	* Katkı Düzeyi
Ad	Açıklama	PC Alt	1	2	3	4	5
LO1	Identify genomic structures in various species.	1.2				X
LO2	Explain traditional and modern genomic techniques.	1.5				X
LO3	Apply comparative genomic applications.	4			X
LO4	Utilize proteomic approaches which are used in investigation of protein structure and function.	1.5				X
LO5	Discuss application areas of genomics and proteomics.	1.5				X

Ders Tanımı

Definition and application areas of genomics and proteomics approaches, structural genomics, functional genomics and usage of comparative genomic, analysis of genomes of livings, proteomic analyses. Recombinant DNA methods, genetically modified plants and animals and their use will be introduced.

Dersin İlişkili Olduğu Sürdürülebilir Kalkınma Amaçları

Dersin Kategorisi	Temel Ders
	Uzmanlık/Alan Dersleri	X
	Destek Dersleri
	İletişim ve Yönetim Becerileri Dersleri
	Aktarılabilir Beceri Dersleri

HAFTALIK KONULAR VE İLGİLİ ÖN HAZIRLIK ÇALIŞMALARI

Hafta	Konular	Ön Hazırlık	Öğrenme Çıktısı
1	Introduction to Genomics	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 1	17ef484c
2	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 1	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 2	17ef484c
3	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 2	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 3,4	17ef484c
4	DNA and Genome sequencing methods	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 5,7	431de204
5	Genome mapping	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 6	5e25ec2f
6	Genome assembly and annotation	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 8	431de204
7	Functional Genomics	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 9	5e25ec2f
8	Midterm I		-
9	Introduction to proteomics	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 10	fb1bb8a6
10	Two-dimensional Gel Electrophoresis	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 11	fb1bb8a6
11	Midterm II		-
12	Mass spectroscopy	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 12	fb1bb8a6
13	Protein identification by peptide mass fingerprinting	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 13	2006c59c
14	Protein sequencing techniques	Concepts and Techniques in Genomics and Proteomics, Nachimuthu Saraswathy, Ponnusamy Ramalingam, Elsevier, 2011, 978-1-907568-10-7. Chapter 14	2006c59c
15	Review of the course		-
16	Final exam		-

Ders Kitabı	Concepts and Techniques in Genomics and Proteomics Nachimuthu Saraswathy- Ponnusamy Ramalingam- Elsevier- 2011. 978-1-907568-10-7
Önerilen Okumalar/Materyaller	-

DEĞERLENDİRME ÖLÇÜTLERİ

Yarıyıl Aktiviteleri	Sayı	Katkı Payı %	LO1	LO2	LO3	LO4	LO5
Küçük Sınav / Stüdyo Kritiği	1	15	X	X
Ödev	1	15				X	X
Ara Sınav	1	30	X	X	X	X
Final Sınavı	1	40		X	X	X	X
Toplam	4	100

AKTS / İŞ YÜKÜ TABLOSU

Yarıyıl Aktiviteleri	Sayı	Süre (Saat)	İş Yükü
Katılım	-	-	-
Teorik Ders Saati	16	2	32
Laboratuvar / Uygulama Ders Saati	16	2	32
Sınıf Dışı Ders Çalışması	14	2	28
Arazi Çalışması	-	-	-
Küçük Sınav / Stüdyo Kritiği	1	20	20
Portfolyo	-	-	-
Ödev	1	24	24
Sunum / Jüri Önünde Sunum	-	-	-
Proje	-	-	-
Seminer/Çalıştay	-	-	-
Sözlü Sınav	-	-	-
Ara Sınavlar	1	22	22
Final Sınavı	1	22	22
		Toplam	180

DERSİN ÖĞRENME ÇIKTILARININ PROGRAM YETERLİLİKLERİ İLE İLİŞKİSİ

#	PC Alt	Program Yeterlilikleri / Çıktıları	* Katkı Düzeyi
#	PC Alt	Program Yeterlilikleri / Çıktıları	1	2	3	4	5
1	Engineering Knowledge: Knowledge of mathematics, science, basic engineering, computation, and related engineering discipline-specific topics; the ability to apply this knowledge to solve complex engineering problems.
	1	Mathematics
	2	Science				LO1
	3	Basic Engineering
	4	Computation
	5	Related engineering discipline-specific topics				LO2 LO4 LO5
	6	The ability to apply this knowledge to solve complex engineering problems
2	Problem Analysis: Ability to identify, formulate and analyze complex engineering problems using basic knowledge of science, mathematics and engineering, and considering the UN Sustainable Development Goals relevant to the problem being addressed.
3	Engineering Design: The ability to devise creative solutions to complex engineering problems; the ability to design complex systems, processes, devices or products to meet current and future needs, considering realistic constraints and conditions.
	1	Ability to design creative solutions to complex engineering problems
	2	Ability to design complex systems, processes, devices or products to meet current and future needs, considering realistic constraints and conditions
4	Use of Techniques and Tools: Ability to select and use appropriate techniques, resources, and modern engineering and computing tools, including estimation and modeling, for the analysis and solution of complex engineering problems, while recognizing their limitations.				LO3
5	Research and Investigation: Ability to use research methods to investigate complex engineering problems, including literature research, designing and conducting experiments, collecting data, and analyzing and interpreting results.
	1	Literature research for the study of complex engineering problems
	2	Designing experiments
	3	Ability to use research methods, including conducting experiments, collecting data. analyzing and interpreting results
6	Global Impact of Engineering Practices: Knowledge of the impacts of engineering practices on society, health and safety, economy, sustainability, and the environment, within the context of the UN Sustainable Development Goals; awareness of the legal implications of engineering solutions.
	1	Knowledge of the impacts of engineering practices on society, health and safety, economy, sustainability, and the environment, within the context of the UN Sustainable Development Goals
	2	Awareness of the legal implications of engineering solutions
7	Ethical Behavior: Acting in accordance with the principles of the engineering profession, knowledge about ethical responsibility; awareness of being impartial, without discrimination, and being inclusive of diversity.
	1	Acting in accordance with the principles of the engineering profession, knowledge about ethical responsibility ethical responsibility
	2	Awareness of being impartial and inclusive of diversity, without discriminating on any subject
8	Individual and Teamwork: Ability to work effectively, individually and as a team member or leader on interdisciplinary and multidisciplinary teams (face-to-face, remote or hybrid).
	1	Ability to work individually and within the discipline
	2	Ability to work effectively as a team member or leader in multidisciplinary teams (face-to-face, remote or hybrid)
9	Verbal and Written Communication: Taking into account the various differences of the target audience (such as education, language, profession) on technical issues.
	1	Ability to communicate verbally
	2	Ability to communicate effectively in writing
10	Project Management: Knowledge of business practices such as project management and economic feasibility analysis; awareness of entrepreneurship and innovation.
	1	Knowledge of business practices such as project management and economic feasibility analysis
	2	Awareness of entrepreneurship and innovation
11	Lifelong Learning: Lifelong learning skills that include being able to learn independently and continuously, adapting to new and developing technologies, and thinking questioningly about technological changes.